Mechanical Left Ventricular Unloading in Patients Undergoing Venoarterial Extracorporeal Membrane Oxygenation.

ABSTRACT:

Background

Venoarterial extracorporeal membrane oxygenation (VA-ECMO) increases left ventricular (LV) afterload, potentially provoking LV distention and impairing recovery. LV mechanical unloading (MU) with intra-aortic balloon pump (IABP) or percutaneous ventricular assist device (pVAD) can prevent LV distension, potentially at the risk of more complications, and net clinical benefit remains uncertain.

Objectives

This study aims to determine the association between MU and outcomes for patients undergoing VA-ECMO.

Methods

The authors queried the Extracorporeal Life Support Organization registry for adults receiving peripheral VA-ECMO from 2010 to 2019 and stratified them by MU with IABP or pVAD. The primary outcome was in-hospital mortality; secondary outcomes include

SUBMITTER: Grandin EW 

PROVIDER: S-EPMC9187498 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature