Magnetization Transfer Ratio of Peripheral Nerve and Skeletal Muscle : Correlation with Demographic Variables in Healthy Volunteers.

ABSTRACT:

Purpose

To assess the correlation of peripheral nerve and skeletal muscle magnetization transfer ratio (MTR) with demographic variables.

Methods

In this study 59 healthy adults evenly distributed across 6 decades (mean age 50.5 years ±17.1, 29 women) underwent magnetization transfer imaging and high-resolution T2-weighted imaging of the sciatic nerve at 3 T. Mean sciatic nerve MTR as well as MTR of biceps femoris and vastus lateralis muscles were calculated based on manual segmentation on six representative slices. Correlations of MTR with age, body height, body weight, and body mass index (BMI) were expressed by Pearson coefficients. Best predictors for nerve and muscle MTR were determined using a multiple linear regression model with forward variable selection and fivefold

SUBMITTER: Fosleitner O 

PROVIDER: S-EPMC9187530 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature