Esophageal abnormalities and the risk for gastroesophageal cancers-a histopathology-register-based study in Sweden.

ABSTRACT:

Background

The poor survival of patients with gastroesophageal cancers may improve if additional esophageal precursor lesions to Barrett's esophagus and squamous dysplasia are identified. We estimated the risk for gastroesophageal cancers among patients with various histopathological abnormalities in the esophagus, including Barrett's esophagus, subdivided by histopathological types.

Methods

Histopathology data from esophageal biopsies obtained 1979-2014 were linked with several national population-based registers in Sweden. Patients were followed from 2 years after the first biopsy date until cancer, death, emigration, esophagectomy/gastrectomy or end of follow-up, 31st of December 2016, whichever came first. We estimated standardized incidence ratios (SIRs) as measures of

SUBMITTER: Ekheden I 

PROVIDER: S-EPMC9187549 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature