A method for the controllable fabrication of optical fiber-based localized surface plasmon resonance sensors.

ABSTRACT: Optical fiber-based Localized Surface Plasmon Resonance (OF-LSPR) biosensors have emerged as an ultra-sensitive miniaturized tool for a great variety of applications. Their fabrication by the chemical immobilization of gold nanoparticles (AuNPs) on the optic fiber end face is a simple and versatile method. However, it can render poor reproducibility given the number of parameters that influence the binding of the AuNPs. In order to develop a method to obtain OF-LSPR sensors with high reproducibility, we studied the effect that factors such as temperature, AuNPs concentration, fiber core size and time of immersion had on the number and aggregation of AuNPs on the surface of the fibers and their resonance signal. Our method consisted in controlling the deposition of a determined AuNPs densit

SUBMITTER: Calatayud-Sanchez A 

PROVIDER: S-EPMC9187767 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature