Oral and Maxillofacial Neuroendocrine Carcinoma: A Systematic Review.

ABSTRACT: The aim of the present study was to integrate the available data published in the literature on oral and maxillofacial neuroendocrine carcinomas concerning the demographic, clinical and histopathological features of this condition. An electronic search with no publication date restriction was undertaken in April 2021 in four databases. Eligibility criteria included reports published in English having enough data to confirm a definite diagnosis, always showing a neuroendocrine marker. Cases originating in the oropharynx, including base of the tongue and tonsils, were excluded. Outcomes were evaluated by the Kaplan-Meier method along with Cox regression. Twenty-five articles (29 cases) from nine different countries were detected. Mean patient age was 56.3 (± 17.5) years, with a slight male p

SUBMITTER: Schuch LF 

PROVIDER: S-EPMC9187797 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature