Implementing OECD GLP principles for the evaluation of novel vector control tools: a case study with two novel LLINs, SafeNet^® and SafeNet NF^®.

ABSTRACT:

Background

To sustain high universal Long-Lasting Insecticidal Nets (LLINs) coverage, affordable nets that provide equivalent or better protection than standard LLINs, are required. Test facilities evaluating new LLINs require compliance to Good Laboratory Practice (GLP) standards to ensure the quality and integrity of test data. Following GLP principles allows for the reconstruction of activities during the conduct of a study and minimizes duplication of efficacy testing. This case study evaluated the efficacy of two LLINs: SafeNet NF^® and SafeNet^® LLIN.

Methods

The study was conducted according to GLP principles and followed World Health Organization guidelines for evaluating LLINs. The LLINs were assessed in experimental huts against wild, pyrethroid

SUBMITTER: Azizi S 

PROVIDER: S-EPMC9188019 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature