Triglyceride-glucose index variability and incident cardiovascular disease: a prospective cohort study.

ABSTRACT:

Background

Recent studies have suggested that triglyceride-glucose (TyG) index is an independent predictor of cardiovascular disease (CVD). However, the impact of long-term visit-to-visit variability in TyG index on the risk of CVD is not known. We aimed to investigate the longitudinal association between baseline and mean TyG index as well as TyG index variability and incident CVD in a Chinese population.

Methods

We included 49,579 participants without previous history of CVD in the Kailuan study who underwent three health examinations (2006, 2008, and 2010) and were followed up for clinical events until 2019. TyG index was calculated as Ln [fasting triglyceride (mg/dL) × fasting glucose (mg/dL)/2]. We measured TyG index variability as the SD of the residuals obtained from

SUBMITTER: Li H 

PROVIDER: S-EPMC9188105 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature