Longitudinal Association Between Oral Status and Cognitive Decline Using Fixed-effects Analysis.

ABSTRACT:

Background

Although the feasibility of randomized trials for investigating the long-term association between oral health and cognitive decline is low, deriving causal inferences from observational data is challenging. We aimed to investigate the association between poor oral status and subjective cognitive complaints (SCC) using fixed-effects model to eliminate the confounding effect of unobserved time-invariant factors.

Methods

We used data from Japan Gerontological Evaluation Study (JAGES) which was conducted in 2010, 2013, and 2016. β regression coefficients and 95% confidence intervals [CIs] were calculated using fixed-effects models to determine the effect of deteriorating oral status on developing SCC. Onset of SCC was evaluated using the Kihon Checklist-Cognitive func

SUBMITTER: Kiuchi S 

PROVIDER: S-EPMC9189315 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature