Age-related changes in mean corpuscular volumes in patients without anaemia: An analysis of large-volume data from a single institute.

ABSTRACT: Although the mean corpuscular volume (MCV) has been associated with various diseases, these associations in relation to the age-related trends in MCV remain unclear. Therefore, we used a dataset with over one million values to identify the relationship between ageing and MCV changes. All laboratory data obtained between November 1998 and November 2019 at Chungbuk National University Hospital were retrospectively collected. After excluding cases with missing values for individual complete blood count parameters, outlier MCV values, and ages less than 1 year and more than 88 years, 977,335 MCV values were obtained from 309,393 patients. Principal component analysis of blood components with ages and analysis of the median value changes for each blood component across decade-wise age groups we

SUBMITTER: Lee JY 

PROVIDER: S-EPMC9189337 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature