A Set of Reliable Samples for the Study of Biomarkers for the Early Diagnosis of Parkinson's Disease.

ABSTRACT:

Background

Parkinson's disease (PD) is a progressive neurodegenerative disorder, diagnosed according to the clinical criteria that occur in already advanced stages of PD. The definition of biomarkers for the early diagnosis of PD represents a challenge that might improve treatment and avoid complications in this disease. Therefore, we propose a set of reliable samples for the identification of altered metabolites to find potential prognostic biomarkers for early PD.

Methods

This case-control study included plasma samples of 12 patients with PD and 21 control subjects, from the Spanish European Prospective Investigation into Cancer and Nutrition (EPIC)-Navarra cohort, part of the EPIC-Spain study. All the case samples were provided by healthy volunteers who were followed-up f

SUBMITTER: Konjevod M 

PROVIDER: S-EPMC9189395 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature