Change in covid-19 risk over time following vaccination with CoronaVac: test negative case-control study.

ABSTRACT:

Objective

To estimate the change in odds of covid-19 over time following primary series completion of the inactivated whole virus vaccine CoronaVac (Sinovac Biotech) in São Paulo State, Brazil.

Design

Test negative case-control study.

Setting

Community testing for covid-19 in São Paulo State, Brazil.

Participants

Adults aged ≥18 years who were residents of São Paulo state, had received two doses of CoronaVac, did not have a laboratory confirmed SARS-CoV-2 infection before vaccination, and underwent reverse transcription polymerase chain reaction (RT-PCR) testing for SARS-CoV-2 from 17 January to 14 December 2021. Cases were matched to test negative controls by age (in 5 year bands), municipality of residence, healthcare worker status, and epidemiological week o

SUBMITTER: Hitchings MDT 

PROVIDER: S-EPMC9189440 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature