Prioritizing Research in an Era of Personalized Medicine: The Potential Value of Unexplained Heterogeneity.

ABSTRACT:

Background

Clinical care is moving from a "one size fits all" approach to a setting in which treatment decisions are based on individual treatment response, needs, preferences, and risk. Research into personalized treatment strategies aims to discover currently unknown markers that identify individuals who would benefit from treatments that are nonoptimal at the population level. Before investing in research to identify these markers, it is important to assess whether such research has the potential to generate value. Thus, this article aims to develop a framework to prioritize research into the development of new personalized treatment strategies by creating a set of measures that assess the value of personalizing care based on a set of unknown patient characteristics.

Methods<

SUBMITTER: Heath A 

PROVIDER: S-EPMC9189719 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature