Calculating Expected Value of Sample Information Adjusting for Imperfect Implementation.

ABSTRACT:

Background

The expected value of sample information (EVSI) calculates the value of collecting additional information through a research study with a given design. However, standard EVSI analyses do not account for the slow and often incomplete implementation of the treatment recommendations that follow research. Thus, standard EVSI analyses do not correctly capture the value of the study. Previous research has developed measures to calculate the research value while adjusting for implementation challenges, but estimating these measures is a challenge.

Methods

Based on a method that assumes the implementation level is related to the strength of evidence in favor of the treatment, 2 implementation-adjusted EVSI calculation methods are developed. These novel methods circumvent

SUBMITTER: Heath A 

PROVIDER: S-EPMC9189720 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature