The health-related quality of life of children with multiple sclerosis is mediated by the health-related quality of life of their parents.

ABSTRACT:

Background

We previously found that children with the chronic disease multiple sclerosis (MS) reported lower health-related quality of life (HRQoL) when compared to children who experienced the transient illness termed monophasic acquired demyelinating syndromes (monoADS). Parents of children with MS also reported lower HRQoL.

Objectives

We evaluated whether parental HRQoL mediated the relationship between the diagnosis of MS and the HRQoL of affected children. To ascertain the effect of an MS diagnosis, we compared children with MS to those with monoADS.

Methods

Children were enrolled in a prospective multi-site Canadian study. Random effects models evaluated whether parental HRQoL mediated the relationship between the diagnosis of MS and the HRQoL of affected childr

SUBMITTER: O'Mahony J 

PROVIDER: S-EPMC9189724 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature