Bidirectional association between glaucoma and chronic kidney disease: A systematic review and meta-analysis.

ABSTRACT:

Background

Glaucoma and chronic kidney disease (CKD) are prevalent and debilitating conditions, with common pathogenic pathways like oxidative stress and fluid dysregulation. We evaluated if there is a bidirectional association between them, as previous studies have yielded conflicting results.

Methods

In this systematic review and meta-analysis, we searched PubMed, Embase and Cochrane Library from inception until 15 June 2021, including full-length English articles published in peer-reviewed journals reporting on glaucoma and CKD as either exposure or outcome, among participants aged ≥18 years. We pooled overall summary estimates of odds ratios using random-effect meta-analysis and conducted subgroup meta-analyses and univariate meta regression. We assessed risk of bias usi

SUBMITTER: Ng FYC 

PROVIDER: S-EPMC9189872 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature