Glycated haemoglobin (HbA1c) in mid-pregnancy and perinatal outcomes.

ABSTRACT:

Background

Maternal diabetes is a well-known risk factor for pregnancy complications. Possible links between long-term maternal blood sugar in the normal range and pregnancy complications are less well described.

Methods

We assayed glycated haemoglobin (HbA1c) in blood samples collected around the 18th week of pregnancy for 2937 singleton pregnancies in the Norwegian Mother, Father and Child Cohort Study (2000-09). Perinatal outcomes (gestational length, birthweight, birth length and head circumference, large-for-gestational age, small-for-gestational age, congenital malformations, preterm delivery and preeclampsia) were obtained from medical records. We tested associations using linear and log-binomial regression, adjusting for maternal age, body mass index (BMI) and smokin

SUBMITTER: Carlsen EO 

PROVIDER: S-EPMC9189945 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature