Dataset Information

Birth outcomes following unexpected job loss: a matched-sibling design.

ABSTRACT:

Background

Research documents social and economic antecedents of adverse birth outcomes, which may include involuntary job loss. Previous work on job loss and adverse birth outcomes, however, lacks high-quality individual data on, and variation in, plausibly exogenous job loss during pregnancy and therefore cannot rule out strong confounding.

Methods

We analysed unique linked registries in Denmark, from 1980 to 2017, to examine whether a father's involuntary job loss during his spouse's pregnancy increases the risk of a low-weight (i.e. <2500 grams) and/or preterm (i.e. <37 weeks of gestational age) birth. We applied a matched-sibling design to 743 574 sibling pairs.

Results

Results indicate an increased risk of a low-weight birth among infants exposed in utero to fathers' unexpected job loss [odds ratio (OR) = 1.37, 95% confidence interval (CI): 1.07, 1.75]. Sex-specific analyses show that this result holds for males (OR = 1.70, 95% CI: 1.14, 2.53) but not females (OR = 1.24, 95% CI: 0.80, 1.91). We find no relation with preterm birth.

Conclusions

Findings support the inference that a father's unexpected job loss adversely affects the course of pregnancy, especially among males exposed in utero.

SUBMITTER: Gailey S

PROVIDER: S-EPMC9189955 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature

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Publications

Birth outcomes following unexpected job loss: a matched-sibling design.

Gailey Samantha S Knudsen Elias Stapput ES Mortensen Laust H LH Bruckner Tim A TA

International journal of epidemiology 20220601 3

<h4>Background</h4>Research documents social and economic antecedents of adverse birth outcomes, which may include involuntary job loss. Previous work on job loss and adverse birth outcomes, however, lacks high-quality individual data on, and variation in, plausibly exogenous job loss during pregnancy and therefore cannot rule out strong confounding.<h4>Methods</h4>We analysed unique linked registries in Denmark, from 1980 to 2017, to examine whether a father's involuntary job loss during his sp ...[more]

PMID: 34508593

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Project description:ObjectiveTo investigate the association between gestational age at birth and cognitive outcomes in adolescence.DesignNationwide population based full sibling cohort study.SettingDenmark.Participants1.2 million children born between 1 January 1986 and 31 December 2003, of whom 792 724 had one or more full siblings born in the same period.Main outcome measuresScores in written language (Danish) and mathematics examinations as graded by masked assessors at the end of compulsory schooling (ninth grade, ages 15-16 years), in addition to intelligence test score at military conscription (predominantly at age 18 years) for a nested sub-cohort of male adolescents. School grades were standardised as z scores according to year of examination, and intelligence test scores were standardised as z scores according to year of birth.ResultsAmong 792 724 full siblings in the cohort, 44 322 (5.6%) were born before 37+0 weeks of gestation. After adjusting for multiple confounders (sex, birth weight, malformations, parental age at birth, parental educational level, and number of older siblings) and shared family factors between siblings, only children born at <34 gestational weeks showed reduced mean grades in written language (z score difference -0.10 (95% confidence interval -0.20 to -0.01) for ≤27 gestational weeks) and mathematics (-0.05 (-0.08 to -0.01) for 32-33 gestational weeks, -0.13 (-0.17 to -0.09) for 28-31 gestational weeks, and -0.23 (-0.32 to -0.15) for ≤27 gestational weeks), compared with children born at 40 gestational weeks. In a nested sub-cohort of full brothers with intelligence test scores, those born at 32-33, 28-31, and ≤27 gestational weeks showed a reduction in IQ points of 2.4 (95% confidence interval 1.1 to 3.6), 3.8 (2.3 to 5.3), and 4.2 (0.8 to 7.5), respectively, whereas children born at 34-39 gestational weeks showed a reduction in intelligence of <1 IQ point, compared with children born at 40 gestational weeks.ConclusionsCognitive outcomes in adolescence did not differ between those born at 34-39 gestational weeks and those born at 40 gestational weeks, whereas those with a gestational age of <34 weeks showed substantial deficits in multiple cognitive domains.

Dataset Information

Birth outcomes following unexpected job loss: a matched-sibling design.

Background

Methods

Results

Conclusions

Publications

Birth outcomes following unexpected job loss: a matched-sibling design.

Similar Datasets

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