Texture signatures of native myocardial T₁ as novel imaging markers for identification of hypertrophic cardiomyopathy patients without scar.

ABSTRACT:

Background

In patients with suspected or known hypertrophic cardiomyopathy (HCM), late gadolinium enhancement (LGE) provides diagnostic and prognostic value. However, contraindications and long-term retention of gadolinium have raised concern about repeated gadolinium administration in this population. Alternatively, native T₁ -mapping enables identification of focal fibrosis, the substrate of LGE. However HCM-specific heterogeneous fibrosis distribution leads to subtle T₁ -maps changes that are difficult to identify.

Purpose

To apply radiomic texture analysis on native T₁ -maps to identify patients with a low likelihood of LGE(+), thereby reducing the number of patients exposed to gadolinium administration.

Study type

Retrospective in

SUBMITTER: Neisius U 

PROVIDER: S-EPMC9190206 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature