Aging-Related Differences in Structural and Functional Interhemispheric Connectivity.

ABSTRACT: There is substantial evidence of age-related declines in anatomical connectivity during adulthood, with associated alterations in functional connectivity. But the relation of those functional alterations to the structural reductions is unclear. The complexities of both the structural and the functional connectomes make it difficult to determine such relationships. We pursue this question with methods, based on animal research, that specifically target the interhemispheric connections between the visual cortices. We collect t1- and diffusion-weighted imaging data from which we assess the integrity of the white matter interconnecting the bilateral visual cortices. Functional connectivity between the visual cortices is measured with electroencephalography during the presentation of drifting s

SUBMITTER: Lewis JD 

PROVIDER: S-EPMC9190305 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature