Dexmedetomidine effect on delirium in elderly patients undergoing general anesthesia: A protocol for systematic review and meta-analysis.

ABSTRACT:

Background

Delirium is a common postoperative complication. Many studies have found that dexmedetomidine is associated with a reduced incidence of postoperative delirium (POD). This meta-analysis aimed to analyze the effects of dexmedetomidine on POD incidence among elderly patients undergoing general anesthesia.

Methods

We searched 4 electronic databases (i.e., Pubmed, Embase, Cochrane, and Web of Science) from inception to November 30, 2020, for randomized controlled trials that evaluated the effects of dexmedetomidine in preventing the occurrence of POD in elderly patients (aged ≥60 years). The study protocol was registered in PROSPERO (CRD42020192114).

Results

14 studies with 4173 patients showed that dexmedetomidine was significantly associated with a decreased P

SUBMITTER: Wang Y 

PROVIDER: S-EPMC9191298 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature