Management of stable coronary artery disease and atrial fibrillation with anti-thrombotic therapy: A systematic review and meta-analysis.

ABSTRACT:

Introduction

Long term management of patients with stable coronary artery disease of >1 year after myocardial infarction (MI) or percutaneous coronary intervention and atrial fibrillation is unclear. Current guidelines recommend using oral anti-coagulation (OAC) alone although the recommendation is weak and there is low quality evidence. Two new randomized control trials (RCTs) were published recently. We conducted an updated meta-analysis to evaluate the effect of these studies on patient outcomes.

Objective

To conduct a systematic review and meta-analysis of published RCTs and observational studies to compare OAC alone versus OAC plus single anti-platelet therapy.

Methods

Electronic searches were conducted using appropriate terms from 3 databases. Relevant studies i

SUBMITTER: Malladi S 

PROVIDER: S-EPMC9191377 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature