The Effect of Alfentanil on Emergence Delirium Following General Anesthesia in Children: A Randomized Clinical Trial.

ABSTRACT:

Background

Emergence delirium can occur after general anesthesia in children. An intravenous infusion of alfentanil may reduce the incidence or severity of emergence delirium after sevoflurane anesthesia.

Objective

The study aimed to investigate the effects of alfentanil intravenous infusion on emergence delirium and other perioperative complications.

Method

This was a single-center, randomized, placebo-controlled, double-blind clinical trial. A total of 172 children undergoing ambulatory dental treatment were randomized into three groups. Alfentanil group Alf2 received 0.2 μg/kg/min of alfentanil for continuous infusion, alfentanil group Alf4 received 0.4 μg/kg/min alfentanil, and the saline group (group Sal) received a continuous infusion of normal saline, with the

SUBMITTER: Zhao N 

PROVIDER: S-EPMC9191756 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature