Predictors of early remission of proteinuria in adult patients with minimal change disease: a retrospective cohort study.

ABSTRACT: Previous studies reported conflicting results regarding an association between serum albumin concentration and the cumulative incidence of remission of proteinuria in adult patients with minimal change disease (MCD). The present study aimed to clarify the clinical impact of serum albumin concentration and the cumulative incidence of remission and relapse of proteinuria in 108 adult patients with MCD at 40 hospitals in Japan, who were enrolled in a 5-year prospective cohort study of primary nephrotic syndrome, the Japan Nephrotic Syndrome Cohort Study (JNSCS). The association between serum albumin concentration before initiation of immunosuppressive treatment (IST) and the cumulative incidence of remission and relapse were assessed using multivariable-adjusted Cox proportional hazards model

SUBMITTER: Yamamoto R 

PROVIDER: S-EPMC9192725 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature