Distinct predictors of short- versus long-term depression outcomes following electroconvulsive therapy.

ABSTRACT: Patients and clinicians considering electroconvulsive therapy (ECT) for treatment-resistant depression are faced with limited information about the likely long-term outcomes, and the individual characteristics that predict those outcomes. We aimed to identify sociodemographic and clinical predictors of acute ECT response and subsequent long-term depression severity. This prospective longitudinal study followed adult patients at a single academic ECT center. Among 114 participants, 105 completed an index ECT series and 70 were classified as acute ECT responders. Over a 2-year follow-up period, 82 subjects provided data on depression severity (Patient Health Questionnaire; PHQ-9). Better acute ECT response was predicted by less medication resistance, shorter index episode, and psychotic feat

SUBMITTER: Mickey BJ 

PROVIDER: S-EPMC9192826 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature