Association of Taste-Related Genes With Diet Quality and Cardiometabolic Risk Factors Among Community-Dwelling Adults – The Framingham Heart Study

ABSTRACT: Abstract

Objectives

Understanding the individual-level drivers of food choices is critical for designing personalized nutrition guidance. Taste perception is one factor, yet the effects of genetic variants (SNPs) related to taste perception on diet quality and cardiometabolic risk factors (CRFs) are unknown. Thus, our aims were to determine the associations of taste-related SNPs, combined as polygenic risk scores (PRS), with diet quality, and CRFs (waist circumference, glucose, systolic and diastolic blood pressure [SBP and DBP], and log[triglyceride] [TG] and HDL levels).

Methods

Cross-sectional analyses were conducted in 6,230 Framingham Heart Study Offspring (1998–2001) and Third Generation (2002–05) participants (mean age ± SD: 50 ± 14 y; 54% female). Diet quality was

SUBMITTER:  

PROVIDER: S-EPMC9194398 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature