Meta-Analysis of Quality of Life in Cancer Patients Treated With Immune Checkpoint Inhibitors.

ABSTRACT:

Background

Trials of immune checkpoint inhibitors (ICIs) have published patient-reported quality of life (QOL), but the size and heterogeneity of this literature can make patient education difficult. This meta-analysis aimed to describe change in QOL and symptomatology in patients receiving ICIs for cancer.

Methods

Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, databases were searched through November 2019 for articles or abstracts of prospective, original studies reporting longitudinal QOL in adult cancer patients treated with ICIs. The prespecified primary outcomes were change in global QOL among patients treated with ICIs and difference in change since baseline in global QOL between patients treated with ICI vs non-ICI active trea

SUBMITTER: Gonzalez BD 

PROVIDER: S-EPMC9194633 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature