Association of Interpregnancy Interval With Adverse Birth Outcomes.

ABSTRACT:

Importance

Many studies have reported an association of interpregnancy interval (IPI) between 2 consecutive births with adverse birth outcomes in low- and middle-income countries. However, most of these studies ignore the implications of some unmeasured confounders.

Objective

To explore the association of IPI with adverse perinatal outcomes.

Design, setting, and participants

This large-scale cohort study used the Guangdong Provincial Women and Children Health Information System in Guangdong Province, China, to obtain birth data recorded between January 1, 2014, and December 31, 2020. Matched-sibling design was used. The final cohort included first-born and second-born sibling pairs delivered by mothers who were permanent residents of Guangdong Province.

Exposures</

SUBMITTER: Xu T 

PROVIDER: S-EPMC9194661 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature