Otolaryngology Manifestations of Primary Ciliary Dyskinesia: A Multicenter Study.

ABSTRACT:

Objective

This project aims to prospectively and objectively assess otolaryngological manifestations and quality of life of children with primary ciliary dyskinesia (PCD) and compare these findings with healthy pediatric controls.

Study design

Cross-sectional.

Setting

Two high-volume pediatric PCD specialty centers.

Methods

Standardized clinical assessment; Sino-Nasal Outcome Test 22 (SNOT-22); Hearing Environment and Reflection Quality of Life (HEAR-QL); Reflux Symptom Index (RSI); standardized physical examination of the sinonasal, laryngeal, and otological systems; and investigations including pure-tone audiograms (PTAs) and sinonasal cultures were collected.

Results

Forty-seven children with PCD and 25 control participants were recruited. Children wi

SUBMITTER: Zawawi F 

PROVIDER: S-EPMC9194911 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature