Definitive local therapy to head and neck squamous cell carcinoma with distant metastasis.

ABSTRACT:

Objectives

Data on the efficacy of including definitive local therapy to the primary site for head and neck squamous cell carcinoma (HNSCC) patients with synchronous distant metastasis are lacking. In multiple different solid tumor types, there has been benefit when using systemic therapy followed by local consolidative therapy (stereotactic ablative radiotherapy or surgery) directed at metastases. We proposed to retrospectively evaluate patients at our institution that received definitive treatment to the primary.

Methods

Single institution retrospective study evaluating 40 patients with metastatic HNSCC treated with definitive surgery (55%) or chemoradiation (45%) to the primary site from 2000 to 2020. The major endpoints were overall survival (OS) and progression-free sur

SUBMITTER: Borson S 

PROVIDER: S-EPMC9194988 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature