Euglycemia after antenatal late preterm steroids: a multicenter, randomized controlled trial.

ABSTRACT:

Background

Late preterm steroid administration can induce transient maternal and thus fetal hyperglycemia, which can increase production of fetal insulin and C-peptide. Infants delivered in this setting are subsequently at increased risk for hypoglycemia. Although maternal glycemic control before delivery is a key component of care for parturients with diabetes, this intervention has not been studied in the setting of late preterm steroid administration.

Objective

This study aimed to determine the effect of maternal screening for and treatment of hyperglycemia after late preterm steroid administration on fetal C-peptide levels and other metabolic markers.

Study design

This was a multicenter, randomized trial (NCT03076775) of nondiabetic parturients with a singleton ge

SUBMITTER: Battarbee AN 

PROVIDER: S-EPMC9195161 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature