Investigation of the optimal platinum-based regimen in the postoperative adjuvant chemotherapy setting for early-stage resected non-small lung cancer: a Bayesian network meta-analysis.

ABSTRACT:

Objective

This study aimed to compare the efficacy and safety of different platinum adjuvant chemotherapy regimens for early-stage resected non-small-cell lung cancer (NSCLC).

Design

Systematic review with network meta-analysis of randomised trials.

Data sources

PubMed, EMBASE, The Cochrane Library, Web of Science and Scopus Google Scholar were searched through 12 March 2021.

Eligibility criteria

Eligible randomised controlled trials (RCTs) comparing the postoperative platinum chemotherapy regimen with the observation-controlled group or comparing two platinum chemotherapy regimens head-to-head were included.

Data extraction and synthesis

The primary outcome was the efficacy of adjuvant chemotherapy regimens including relapse-free survival (RFS), overall

SUBMITTER: Pang LL 

PROVIDER: S-EPMC9196189 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature