Preintubation Sequential Organ Failure Assessment Score for Predicting COVID-19 Mortality: External Validation Using Electronic Health Record From 86 U.S. Healthcare Systems to Appraise Current Ventilator Triage Algorithms.

ABSTRACT:

Objectives

Prior research has hypothesized the Sequential Organ Failure Assessment (SOFA) score to be a poor predictor of mortality in mechanically ventilated patients with COVID-19. Yet, several U.S. states have proposed SOFA-based algorithms for ventilator triage during crisis standards of care. Using a large cohort of mechanically ventilated patients with COVID-19, we externally validated the predictive capacity of the preintubation SOFA score for mortality prediction with and without other commonly used algorithm elements.

Design

Multicenter, retrospective cohort study using electronic health record data.

Setting

Eighty-six U.S. health systems.

Patients

Patients with COVID-19 hospitalized between January 1, 2020, and February 14, 2021, and subsequently init

SUBMITTER: Keller MB 

PROVIDER: S-EPMC9196924 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature