Priority-based transformations of stimulus representation in visual working memory.

ABSTRACT: How does the brain prioritize among the contents of working memory (WM) to appropriately guide behavior? Previous work, employing inverted encoding modeling (IEM) of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) datasets, has shown that unprioritized memory items (UMI) are actively represented in the brain, but in a "flipped", or opposite, format compared to prioritized memory items (PMI). To acquire independent evidence for such a priority-based representational transformation, and to explore underlying mechanisms, we trained recurrent neural networks (RNNs) with a long short-term memory (LSTM) architecture to perform a 2-back WM task. Visualization of LSTM hidden layer activity using Principal Component Analysis (PCA) confirmed that stimulus representation

SUBMITTER: Wan Q 

PROVIDER: S-EPMC9197029 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature