Uric Acid and Diabetic Retinopathy: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

The relationship between uric acid (UA) and diabetic retinopathy (DR) remains ambiguous, and the results of current studies on the UA levels in patients with DR are conflicting. A meta-analysis was performed to provide a better understanding of the relationship between UA levels and DR.

Methods

PubMed, Web of Science, Embase, and the Cochrane Library databases were searched until December 11, 2021 to identify eligible studies, that compared the UA levels of the case group (patients with DR) and control group (controls with diabetes and healthy participants). The weighted mean difference (WMD) with a 95% confidence interval (CI) was used to evaluate the difference in UA levels between the case and control groups.

Results

Twenty-one studies involving 4,340 pa

SUBMITTER: Guo Y 

PROVIDER: S-EPMC9197488 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature