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Pursuing totipotency: authentic totipotent stem cells in culture.


ABSTRACT: Totipotent stem cells are transiently occurring in vivo cells that can form all cell types of the embryo including placenta, with their in vitro counterparts being actively pursued. Subsequently, totipotent-like cells are established with variable robustness and biological relevance. Here, we summarize current progress on capturing these cells in culture.

SUBMITTER: Malik V 

PROVIDER: S-EPMC9197991 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature

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Pursuing totipotency: authentic totipotent stem cells in culture.

Malik Vikas V   Wang Jianlong J  

Trends in genetics : TIG 20220418 7


Totipotent stem cells are transiently occurring in vivo cells that can form all cell types of the embryo including placenta, with their in vitro counterparts being actively pursued. Subsequently, totipotent-like cells are established with variable robustness and biological relevance. Here, we summarize current progress on capturing these cells in culture. ...[more]

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