Statically controlled mycogenic-synthesis of novel biologically active silver-nanoparticles using Hafr Al-Batin desert truffles and its antimicrobial efficacy against pathogens.

ABSTRACT: In our search for new unconventional green-reducing agent, can be applied for biosynthesis of biologically active silver-nanoparticles, fruiting bodies (Ascocarps) of Truffle Terminia sp. were collected from the sandy desert of Hafr Al-Batin, Eastern Region, Saudi Arabia. The desert truffle showed the ability to reduce AgNO₃ to Ag⁰ depending on their high content of proteins (1.74 mg/ml) in the aqueous extract of 30 mg/ml (w/v). The response surface methodology (RSM) with 13 experiments of 2-Factors-5-Levels central composite design was applied for controlling all possible combinations of AgNO₃ concentrations and pH values of reaction mixture, which directly affect the particles morphology, size and biological activity. The antimicrobial effectivenes

SUBMITTER: Alshammari SO 

PROVIDER: S-EPMC9198477 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature