Nationwide multidisciplinary consensus on the clinical management of Merkel cell carcinoma: a Delphi panel.

ABSTRACT: Merkel cell carcinoma (MCC) is a rare and highly aggressive cutaneous neuroendocrine carcinoma. The MCC incidence rate has rapidly grown over the last years, with Italy showing the highest increase among European countries. This malignancy has been the focus of active scientific research over the last years, focusing mainly on pathogenesis, new therapeutic trials and diagnosis. A national expert board developed 28 consensus statements that delineated the evolution of disease management and highlighted the paradigm shift towards the use of immunological strategies, which were then presented to a national MCC specialists panel for review. Sixty-five panelists answered both rounds of the questionnaire. The statements were divided into five areas: a high level of agreement was reached in the a

SUBMITTER: Spada F 

PROVIDER: S-EPMC9198700 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature