Gene fusion as an important mechanism to generate new genes in the genus Oryza.

ABSTRACT:

Background

Events of gene fusion have been reported in several organisms. However, the general role of gene fusion as part of new gene origination remains unknown.

Results

We conduct genome-wide interrogations of four Oryza genomes by designing and implementing novel pipelines to detect fusion genes. Based on the phylogeny of ten plant species, we detect 310 fusion genes across four Oryza species. The estimated rate of origination of fusion genes in the Oryza genus is as high as 63 fusion genes per species per million years, which is fixed at 16 fusion genes per species per million years and much higher than that in flies. By RNA sequencing analysis, we find more than 44% of the fusion genes are expressed and 90% of gene pairs show strong signals of purifying selection. Furt

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC9199173 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature