Sex differences in the human metabolome.

ABSTRACT:

Background

The sexual dimorphism represents one of the triggers of the metabolic disparities between the organisms, advising about wild implications in research or diagnostics contexts. Despite the mounting recognition of the importance of sex consideration in the biomedical fields, the identification of male- and female-specific metabolic signatures has not been achieved.

Main body

This review pointed the focus on the metabolic differences related to the sex, evidenced by metabolomics studies performed on healthy populations, with the leading aim of understanding how the sex influences the baseline metabolome. The main shared signatures and the apparent dissimilarities between males and females were extracted and highlighted from the metabolome of the most commonly analyzed

SUBMITTER: Costanzo M 

PROVIDER: S-EPMC9199320 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature