Physical activity and acute exercise benefit influenza vaccination response: A systematic review with individual participant data meta-analysis.

ABSTRACT: Whether the vaccine adjuvant potential of acute exercise is uniform among different populations, e.g., inactive persons, is unknown. This meta-analysis examines influenza vaccine antibody responses and the effect of physical activity, acute exercise, and their interaction. Inclusion criteria comprised randomized controlled trials with acute exercise intervention and influenza vaccination antibody measurements at baseline and 4-6 weeks, and participant baseline physical activity measurement; there were no exclusion criteria. Searching via six databases (Medline, Embase, CINAHL, Scopus, Web of Science, and Physiotherapy Evidence) and two clinical registries (WHO and NIH), nine studies were identified and assessed with the Cochrane revised risk-of-bias tool. Data analysis comprised one-stage

SUBMITTER: Bohn-Goldbaum E 

PROVIDER: S-EPMC9200169 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature