Decreased salivary α-amylase activity responding to citric acid stimulation in Myasthenia gravis with malnutrition.

ABSTRACT:

Objectives

Malnutrition, defined according to Nutritional risk screening (NRS 2002), is commonly observed in patients of Myasthenia gravis (MG), a neuromuscular disorder manifested by varied degrees of skeletal muscle weakness. Because biochemical composition of saliva changes in correspondence to alterations in nutritional status, we tested our hypothesis that a certain saliva component(s) might serve as a biomarker(s) for nutrition status of MG, particularly for those MG patients with high risk of malnutrition.

Materials and methods

60 MG patients and 60 subjects belonging to the healthy control group (HCG) were enrolled in this case-control study. The salivary α-amylase (sAA) activity, salivary flow rate (SFR), pH, total protein density (TPD), and the concentrations of ch

SUBMITTER: Huang Y 

PROVIDER: S-EPMC9200330 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature