Clinical impact of statin intensity according to age in patients with acute myocardial infarction.

ABSTRACT:

Background

The available data are not sufficient to understand the clinical impact of statin intensity in elderly patients who undergo percutaneous coronary intervention (PCI) due to acute myocardial infarction (AMI).

Methods

Using the COREA-AMI registry, we sought to compare the clinical impact of high- versus low-to-moderate-intensity statin in younger (<75 years old) and elderly (≥75 years old) patients. Of 10,719 patients, we included 8,096 patients treated with drug-eluting stents. All patients were classified into high-intensity versus low-to-moderate-intensity statin group according to statin type and dose at discharge. The primary end point was target-vessel failure (TVF), a composite of cardiovascular death, target-vessel MI, or target-lesion revascularization (TLR)

SUBMITTER: Lee K 

PROVIDER: S-EPMC9200343 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature