Adherence to additional medication for management of HIV-associated comorbidities among older children and adolescents taking antiretroviral therapy.

ABSTRACT:

Background

Management of co-morbidities among persons living with HIV is an emerging priority, which may require additional medication over and above life-long antiretroviral therapy (ART). We explored factors associated with adherence to the trial drug among children and adolescents with perinatally acquired HIV taking antiretroviral therapy (ART) in the Bronchopulmonary Function in Response to Azithromycin Treatment for Chronic Lung Disease in HIV-Infected Children (BREATHE) trial.

Methods

The BREATHE trial recruited 6-19 year olds with perinatally acquired HIV and co-morbid chronic lung disease as measured by FEV1. This two-site trial was individually randomised (1:1), double-blind and placebo-controlled. Participants received a once-weekly weight-based dose of 1-5 tablet

SUBMITTER: Rehman AM 

PROVIDER: S-EPMC9200347 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature