Proteomic insight into the venom composition of the largest European rear-fanged snake, Malpolon monspessulanus monspessulanus.

ABSTRACT: Snake envenomations constitute a worldwide neglected tropical disease, with the vast majority of lethal bites inflicted by front-fanged snakes from the viperid and elapid groups. Rear-fanged snakes (colubrids) were often considered harmless and as a result, are much less studied, but several documented deaths have suggested potent venom in this group as well. The largest European snake (Malpolon monspessulanus monspessulanus), known as the "Montpellier snake", is such a rear-fanged snake that belongs to the Lamprophiidae family. Its venom remains largely unknown but cases of envenomation with neurological symptoms have been reported. Here, we provide the first insights into the composition of its venom using mass spectrometry methods. First, liquid chromatography coupled mass spectr

SUBMITTER: Koua D 

PROVIDER: S-EPMC9201006 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature