A Novel and Easy-to-Promote Prognostic Model for Patients With Uveal Melanoma.

ABSTRACT:

Purpose

To establish an easy and widely applicable prognostic prediction model for uveal melanoma (UM) based on a Chinese population.

Patients and methods

A total of 295 consecutive cases treated at the Eye & ENT Hospital of Fudan University were included as the primary cohort, and 256 cases were included in the validation cohorts from two external Caucasian databases. Clinicopathological data were collected retrospectively, and nomogram models were formulated based on multivariable analysis. The concordance index (C-index), AUC (area under the Receiver Operating Characteristic, ROC curve), and Brier score were calculated and compared.

Results

Based on the training cohort, a nomogram model was established with five relevant variables: age, tumor size, ciliary body inv

SUBMITTER: Yue H 

PROVIDER: S-EPMC9201029 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature