Progress Toward a Multiomic Understanding of Traumatic Brain Injury: A Review.

ABSTRACT: Traumatic brain injury (TBI) is not a single disease state but describes an array of conditions associated with insult or injury to the brain. While some individuals with TBI recover within a few days or months, others present with persistent symptoms that can cause disability, neuropsychological trauma, and even death. Understanding, diagnosing, and treating TBI is extremely complex for many reasons, including the variable biomechanics of head impact, differences in severity and location of injury, and individual patient characteristics. Because of these confounding factors, the development of reliable diagnostics and targeted treatments for brain injury remains elusive. We argue that the development of effective diagnostic and therapeutic strategies for TBI requires a deep understanding

SUBMITTER: Kocheril PA 

PROVIDER: S-EPMC9201320 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature