Precise Topology of Adjacent Domain-General and Sensory-Biased Regions in the Human Brain.

ABSTRACT: Recent functional MRI studies identified sensory-biased regions across much of the association cortices and cerebellum. However, their anatomical relationship to multiple-demand (MD) regions, characterized as domain-general due to their coactivation during multiple cognitive demands, remains unclear. For a better anatomical delineation, we used multimodal MRI techniques of the Human Connectome Project to scan subjects performing visual and auditory versions of a working memory (WM) task. The contrast between hard and easy WM showed strong domain generality, with essentially identical patterns of cortical, subcortical, and cerebellar MD activity for visual and auditory materials. In contrast, modality preferences were shown by contrasting easy WM with baseline; most MD regions showed visual

SUBMITTER: Assem M 

PROVIDER: S-EPMC9201597 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature