Integrative Analysis of Metabolome and Transcriptome Reveals the Mechanism of Flavonoid Biosynthesis in Lithocarpus polystachyus Rehd.

ABSTRACT: Lithocarpus polystachyus Rehd has received great attention because of its pharmacological activities, such as inhibiting oxidation and lowering blood glucose and blood pressure, and flavonoids are one of its main pharmacodynamic components. It is important to understand the mechanisms of the flavonoid biosynthetic pathway of L. polystachyus, but the regulation of flavonoid biosynthesis is still unclear. In this study, differentially expressed genes and differentially accumulated metabolites in L. polystachyus were studied by integrating transcriptomics and metabolomics technologies. We confirmed the key genes involved in the flavonoid biosynthesis of L. polystachyus, including LpPAL3, LpCHS1, LpCHS2, LpCHI2, and LpF3H, which ha

SUBMITTER: Zhang D 

PROVIDER: S-EPMC9202069 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature