Characterization of Foveal Development in Treatment-Naive Extremely Preterm Infants.

ABSTRACT:

Objective

To characterize and quantify foveal development in treatment-naïve extremely preterm infants using optical coherence tomography.

Methods

In this cross-sectional study, eyes treated for retinopathy of prematurity before imaging were excluded. Inner retinal thickness and outer retina thickness at foveal center and foveal rim were assessed. Extremely preterm (EPT, <28 weeks gestational age) eyes were compared with infants more than 28 weeks of gestation using a multivariable dimension reduction analysis (principal component analysis) and a bilinear factor mode analysis (partial least square discriminant analysis) to determine group intervariability. Further analyses were performed to investigate the effects of gestation on foveal development.

Results

Twenty-six

SUBMITTER: He Y 

PROVIDER: S-EPMC9202331 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature