Experimental Pain Phenotype Profiles in Community-dwelling Older Adults.

ABSTRACT:

Objectives

Pain sensitivity and the brain structure are critical in modulating pain and may contribute to the maintenance of pain in older adults. However, a paucity of evidence exists investigating the link between pain sensitivity and brain morphometry in older adults. The purpose of the study was to identify pain sensitivity profiles in healthy, community-dwelling older adults using a multimodal quantitative sensory testing protocol and to differentiate profiles based on brain morphometry.

Materials and methods

This study was a secondary analysis of the Neuromodulatory Examination of Pain and Mobility Across the Lifespan (NEPAL) study. Participants completed demographic and psychological questionnaires, quantitative sensory testing, and a neuroimaging session. A Principal

SUBMITTER: Wilson AT 

PROVIDER: S-EPMC9202441 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature